Doctor Profile

Luca Cicalese
MD

Luca Cicalese
MD

University of Texas Medical Branch
301 University Boulevard, 6th Floor
Galveston, TX 77555

Galveston

Texas (TX)

Contact Contact Luca Cicalese
T: 409-692-2857
F: 409-747-0777

Visit: www.utmbhealth.com
Transplant Surgery; Surgery, General

Transplant Surgery

Surgery, General

Languages Spoken: English, Italian

Profile

Dr. Cicalese is a Professor of Surgery, John Sealy Distinguished Chair in Transplantation Surgery and the Director of the Texas Transplant Center and Hepatobiliary Surgery at the University of Texas Medical Branch in Galveston.

Dr. Cicalese received his medical degree at the University of Rome, “La Sapienza” in Rome Italy, where he also completed his residency in General Surgery. He then completed his fellowship in Transplant Surgery at the University of Pittsburgh where was also a faculty as Instructor of Surgery for several year. He moved on to the University of Illinois at Chicago where he was an Assistant Professor of Surgery and the Director of the Intestinal transplant and pediatric liver transplant programs and the director of transplant research. Dr. Cicalese then moved to the University of Massachusetts as an Associate Professor of Surgery and as director of the Liver and Intestinal Transplant Programs where he started successful liver transplant program and performed the first successful intestinal transplant in New England. In 2008, he was recruited at the University of Texas as Director of the Texas Transplant Center.

Dr. Cicalese is a surgeon with over twenty years of experience in liver cancer and organ transplantation and has extensive experience in research. He has published over 100 articles in peer review scientific journals and received many awards in his career for his research, clinical and educational accomplishments. Among them, he was recognized as one of the best 10 physicians in the Houston region in 2009 by the Houston Medical Journal and as one of the top Italian researchers working abroad in 2010 by the Italian Ministry of Health. Dr. Cicalese serves in several scientific and academic committees, study sessions and review committees for several surgical and transplant scientific journals. He is PI or CO-I in numerous grants and clinical trials.

 

Published In:

Texas Super Doctors 2026
Texas Super Doctors 2013

About Luca Cicalese

Graduation Year: 1990

Honors and Awards:

Conceded eminence license in Texas, 2022

2011                DISTINGUISHED FELLOWS RESEARCH SYMPOSIUM, AST/CST

2011                AST/CST 2011 TRAVEL AWARD; Mont-Tremblant, Quebec, CA. March 2, 2011; Zorzi D, Elias G, Rasetllini C, Duchini A, Cicalese L.  MELD Score Underestimates Mortality Rate of Liver Transplant Candidates Residing in Specific Geographic Areas:  An Analysis of the Organ Procurement and Transplantation Network/United Network of Organ Sharing (OPTN/UNOS) Database.

2011                BASIC SCIENCE RESEARCH AWARD – Singleton Surgical Sodiety. Zorzi D, Phan T, Lin Y, Cicalese L, Rastellini C, Islet Sixe Affects Engraftment in Pancreatic Islet Transplantation.  Oral presentation at 58th Singleton Surgical Society, Galveston, TX

2011                POSTER OF DISTINCTON AWARD, 2011 American Transplant Congress, Philadelphia, PA, April 30 – May 4, 2011.  ATC 2011: Zorzi D, Elias G, Nseir H, Rastellini C, Duchini A, Cicalese L.  Basiliximab/Mycophenolate Sodium/Low Dose Calcineurin Inhibitor Steroid Free Immunosuppression Protocol Reduces First Year Recurrence Rate of Hepatitis-C F ollowing Liver Transplantation

2010                “ONE OF THE TOP ITALIAN HEALTH RESEARCHERS WORKING ABROAD; INAUGURAL MEMBER OF THE ITALIAN NETWORK OF HEALTH RESEARCH”.  Recognized by the Italian Minister of Health, Prima Conferenza Nazionale sulla Ricerca Sanitaria, Cernobbio, Italy

2009                Houston Medical Journal recognizes the Best of the Best Physiscian in the region. Dr Cicalese was among the 10 physicians recognized as Best of the Best for 2009.

2003                “ONE OF 200 BEST PRESENTATION AWARD” XXX Internatinal Congress of The Transplantation Society, Vienna, Austria

2001                 Terry and Thelma Stergios Award for excellence in basic research for faculties at the University of Illinois.

2001                Urban Health Program and Temple University School of Medicine. Outstanding service in mentoring and training students in the biomedical sciences.

2001                Young Investigator Award for the study: Corticosteroids enhance hepatic injury following ischemia/reperfusion Sileri P, Schena S, Rastellini C, Benedetti E, Cicalese L. Transplant Odyssey 2001, Istanbul, Turkey.

2000                Class Act Award from University of Illinois at Chicago Medical Center. Criteria for the award: "This employee is a role model who continuously demonstrates exceptional competence and compassion in the performance of his/her job responsibilities".

1999                American Society of Transplant Surgeons, 25th Annual Meeting, Chicago, IL, May 19-21. Young Investigator Award for the study: Bacterial translocation in intestinal transplant recipients. Cicalese L, Sileri P, Green M, Abu-Elmagd K, Fung JJ, Starzl TE, Reyes J.

1998                The Transplantation Society, XVII World Congress, Montreal, Canada, July 1998, Travel Award for the study: Translocation of bacteria from the GI tract: protection afforded by lisofylline. Cicalese L, Yacoub W, Rogers JJ, Fung JJ, Rao AS, Starzl TE.

1996                Ross Resident and Fellow research Award Annual Society for Surgery of the Alimentary Tract for the study: Preservation Injury and Acute Rejection of Small Bowel Grafts in the Rat: Protection Afforded by Pyruvate. Cicalese L, Subbotin V, Rastellini C, Rao AS, Stanko RT. Presented in San Francisco, CA at the Society of Surgery for the Alimentary Tract.

1996                Recognized Outstanding Researcher Status from the Immigration and Naturalization Services of the United States of America.

1995                International Steering Committee Fellow Award for the study: Ischemia/reperfusion injury to the rat jejunal muscularis and its innervation is significantly decreased after leukocyte depletion with cyclophosphamide. Cicalese L, Martin JA, Bauer AJ Presented in Rome, Italy at the XV International Symposium on Gastrointestinal Motility.

1995                Specialized in General Surgery Summa cum Laude (70/70 e lode)

1995                Ross Resident and Fellow research Award; Tenth annual Society for Surgery of the Alimentary Tract for the study: Pyruvate prevents post-ischemic mucosal reperfusion injury of the rat small bowel.Cicalese L, Stanko R, Lee KKW, Schraut W. Presented in San Diego, CA at the Society of Surgery for the Alimentary Tract.

1994                American Motility Society Young Investigator Award for the study: Immunology and functional sequelae of acute rejecting rat small intestinal allografts.Cicalese L, Halfter W, Heeckt PF, Schraut WH, Bauer AJ Presented in Wintergreen, VA, at The Eighth Biennial Symposium of the American Motility Society.

1990 - 1991     Hesperis Scholarship, “European College of Transplantation”

1990               Graduated in Medicine Summa cum Laude (110/110 e lode)

 

Publications, Lectures and Presentations:

  1. Tivantinib for second-line treatment of advanced hepatocellular carcinoma: a randomised, placebo-controlled phase 2 study.Santoro A, Rimassa L, Borbath I, Daniele B, Salvagni S, Van Laethem JL, Van Vlierberghe H, Trojan J, Kolligs FT, Weiss A, Miles S, Gasbarrini A, Lencioni M, Cicalese L, Sherman M, Gridelli C, Buggisch P, Gerken G, Schmid RM, Boni C, Personeni N, Hassoun Z, Abbadessa G, Schwartz B, Von Roemeling R, Lamar ME, Chen Y, Porta C.       Lancet Oncology. 2013 Jan;14(1):55-63. doi: 10.1016/S1470-2045(12)70490-4.
  2. Zorzi D, Phan T, Freeman D, Cicalese L, Rastellini C.  Improving Pancreatic Islet Engraftment through Manipulation of Their Size. American Journal of Transplantation,– 2013, May; 5(13): 239-40
  3. Zorzi D, Rastellini C, Freeman D, Elias G, Duchini A, Cicalese, L. Increase in Mortality Rate of Liver Transplant Candidates Residing in Specific Geographic Areas:  Analysis of UNOS Data.  American Journal of Transplantation – 2012, August; 12(8):2188-97
  4. Guturu P, Cicalese L, Duchini A. Hepatitis A vaccination in healthcare personnel. Ann Hepatol. 2012 May-Jun;11(3):326-9, 2012
  5. La Scalia G, Aiello G, Rastellini C, Cicalese L. Standardization of islet isolation outcome – A new automatic system to determine pancreatic islet viability. Expert Syst. Appl. 38(4): 3461-3466 (2011)1.
  6. La Scalia G, Aiello G, Rastellini C, Micale R, Cicalese L. Multi-Criteria Decision Making support system for pancreatic islet transplantation.  Expert Syst. Appl. 38(4): 3091-3097 (2011)
  7. Morini S, Elias G, Brown M, Subbotin V, Rastalleni C, Cicalese L.  Chronic morpho-functional damage as a consequence of transient ischemia/reperfusion injury of the small bowel.  Histol Histopathol. 2010 Mar., 25(3):277-86.
  8. Liang Y, Shilagard T, Xiao SY, Snyder N, Lau D, Cicalese L, Weiss H, Vargas G, Lemon SM. Visualizing Hepatitis C Virus Infections in Human Liver by Two-Photon Microscopy. Gastroenterology, 2009 Jul 23.
  9. Bradley S, Banner B, Elias G, Pahari M, Brown M, Rastellini C, Cicalese L. Genetic expression profile during acute vellular rejection in clinical intestinal transplantation. Transplantation, 2008 Oct 15; 86(7):998-1001.
  10. Elias G, Rastellini C, Nsier H, Nazarey P, Brown M, Pahari M, Shick L, Kim D, Cicalese L. Successful long-term repair of hepatic artery pseudoaneurysm following liver transplantation with primary stent-grafting. Liver Transpl. 2007 Sep 13(9):1346-8.
  11. Pahari MP, Brown ML, Elias G, Nseir H, Banner B, Rastellini C, Cicalese L. Development of a bioartificial new intestinal segment using an acellular matrix scaffold. Gut. 2007 Jun;56(6):885-6.
  12. Morini S, Brown ML, Cicalese L, Elias G, Carotti S, Gaudio E, Rastellini C. Revascularization and remodelling of pancreatic islets grafted under the kidney capsule.J Anat. 2007 May; 210(5):565-77.
  13. Morini S, Braun M, Onori P, Cicalese L, Elias G, Gaudio E, Rastellini C. Morphological changes of isolated rat pancreatic islets: a structural, ultra-structural and morphometric study. J Anat, 2006;209(3):381-392.
  14. Rastellini C, Brown M, Cicalese L.  Heparin-induced thrombocytopenia following pancreatectomy and islet auto-transplantation. Clin Transpl. 2006;20:156-158.
  15. Morini S, Brown M, Onori P, Cicalese L, Elias G, Gaudio E, Rastellini C. Morphological features of isolated pancreatic islets. Structural, ultra-structural and morphometrical study. J Anat, 209(3):381-392, 2006.
  16. Pahari M, Raman A, Bloomenthal A, Costa MA, Elkady W, Banner B, Rastellini C, Cicalese L. A novel approach for intestinal elongation using an acellular dermal matrix.  Transplant Proc. 38(6):1849-50, 2006.
  17. Bradley SP, Pahari M, Misra MV, Uknis ME, Rastellini C, Cicalese L. Intragraft gene expression profile during acute cellular rejection in clinical small bowel transplantation Transplant Proc. 38(6):1740-1, 2006.
  18. Bradley SP, Pahari M, Uknis ME, Rastellini C, Cicalese, L.  Gene expression profiles characterize early graft response in living donor small bowel transplantation.  Transplant Proc. 38(6):1742-3, 2006.
  19. Asham E, Uknis ME, Ratellini C, Elias G, Cicalese L. Acellular dermal matrix provides a good option for abdominal wall closure following small bowel transplantation.  Transplant Proc. 38(6):1770-1, 2006.
  20. Misra MV, Bhattacharya K, Nompleggi DJ, Uknis ME, and Cicalese L. Magnification endoscopy as a reliable tool for the early diagnosis of rejection in living-related small bowel transplants.  IXth International Small Bowel Transplantation Symposium, Brussels, Belgium, June 30-July 2, 2005. Transplant Proc 38(6):1738-9, 2006.
  21. Cicalese L. Management of complex vascular access in intestinal transplantation:  should we wait for it?  Transplantation. 79(12):1644, 2005.
  22. Bradley SP, Kowalik TF, Rastellini C, da Costa MA, Bloomenthal AB, Cicalese L, BasadonnaGP, Uknis ME.  Successful incorporation of short-interfering RNA into islet cells by in situ perfusion.  Transplant Proc, 37(1):233-236, 2005.
  23. Canete JJ, Aidlen JT, Uknis ME, Cicalese L. Images of interest.  Hepatobiliary and pancreatic:  biliary cast syndrome.  J. Gastroenterol Hepatol. 20(5):791, 2005.
  24. Brown ML, Braun M,Cicalese L., Rastellini C.  Effect of perioperative antioxidant therapy on suboptimal islet transplantation in rats.  Transplant Proc 37(1):217-219, 2005.
  25. Bradley SP, Rastellini C, da Costa, MA, Kowalik TF, Bloomenthal AB, Brown M, Cicalese L, Basadonna GP, Uknis ME.  Gene silencing in the endocrine pancreas mediated by short-interfering RNA.  Pancreas 31(4):373-9, 2005.
  26. Brown M, Braun M, Cicalese L, Rastellini C. Effect of perioperative antioxidant therapy on suboptimal islet transplantation in rats. Transplant Proc 37(1):217-219, 2005.
  27. Bradley SP, Kowalik TF, Rastellini C, da Costa MA, Bloomenthal AB, Cicalese L, Basadonna GP, Uknis ME. Successful incorporation of short-interfering RNA into islet cells by in situ perfusion.  Transplant Proc 37(1):233-6, 2005.
  28. Tzoracoleftherakis E, Cohen M, Sileri P, Cicalese L, Benedetti E. Small bowel transplantation and staged abdominal wall reconstruction after shotgun injury. J Trauma 53(4):770-6, 2002.
  29. Horgan S, Vanuno D, Sileri P, Cicalese L, Benedetti E. Robotic-assisted laparoscopic donor nephrectomy for kidney transplantation. Transplantation 15;73(9):1474-9, 2002.
  30. Pirenne J, Verleden G, Nevens F, Delcroix M, Van Raemdonck D, Meyns B, Herijgers P, Daenen W, De Leyn P, Aerts R, Coosemans W, Decaluwe H, Koek G, Vanhaecke J, Schetz M, Verhaegen M, Cicalese L, Benedetti E. Combined liver and (heart-)lung transplantation in liver transplant candidates with refractory portopulmonary hypertension. Transplantation 73(1):140-2, 2002.
  31. Baum CL, Thielke K, Westin E, Kogan E, Cicalese L, Benedetti E. Predictors of weight gain and cardiovascular risk in a cohort of racially diverse kidney transplant recipients.  Nutrition. 18(2):139-46, 2002.
  32. Cicalese L, Sileri P, Gonzales O, Asolati M, Rastellini C, Abcarian H, Benedetti E. Cost-effectiveness of early living related segmental bowel transplantation as therapy for trauma induced irreversible intestinal failure. Transplant Proc 33(7-8):3581-2, 2001.
  33. Cicalese L, Sileri P, Rastellini C, Abcarian H, Benedetti E.  Living related small bowel transplantation.  Graft 4(8):526-534, 2001.
  34. Sileri P, Jao W, Holaysan J, Morini S, Chejfec G, Rastellini C, Abcarian H, Benedetti E, Cicalese L. Mucosal morphological changes of intestinal transplant recipient with severe cholestasis.  Transplant Proc 2002 34(3):925, 2002.
  35. Sileri P, Morini S, Schena S, Rastellini C, Abcarian H, Benedetti E, Cicalese L. Intestinal ischemia/reperfusion injury produces chronic abnormalities of absorptive function. Transplant Proc 34(3):984, 2002.
  36. Cicalese L, Sileri P, Coady N, Asolati M., Rastellini C, Abcarian H, Benedetti E. Proposed protocol to reduce bacterial infectious complications in living related small bowel transplant recipients.  Transplant Proc 34(3):950, 2002.
  37. Rovera GM, Sileri P, Rastellini C, Knight P, Benedetti E, Cicalese L. Quality of life after living related small bowel transplantation. Transplant Proc 34(3):967-8, 2002.
  38. Cicalese L, Sileri P, Rastellini C, Abcarian H, Benedetti E.  Early living related segmental intestinal transplantation for trauma induced ultra-short gut syndrome. Transplant Proc 34(3):914, 2002.
  39. Sileri P, Jao W, Holaysan J, Morini S, Chejfec G, Rastellini C, Abcarian H, Benedetti E, Cicalese L. Mucosal morphologic changes of intestinal transplant recipients with severe cholestasis.  Transplant Proc 34(3):925,v 2002.
  40. Sileri P, Morini S, Sica GS, Schena S, Rastellini C, Gaspari AL, Benedetti E, Cicalese L. Bacterial translocation and intestinal morphological findings in jaundiced rats. Dig Dis Sci 47(4):929-934, 2002.
  41. Raofi V, Cicalese L, Lutrin F, Ruiz O, Westin E, Mork G, Murray J, Hurley F, Ofek B, Dunn TB, Milewski S, Massad MG, Benedetti E. Rapid core cooling with cardiopulmonary bypass and University of Wisconsin solution as a new method of kidney procurement from non-heart beating donors. Intern J Surg Invest 36: 483-489, 2001.
  42. Cicalese L, Rastellini C, Sileri P, Abcarian H, Benedetti E.  Segmental living related small bowel transplantation in adults.  J Gastrointest Surg 5(2):168-173, 2001.
  43. Rastellini C, Li X, Braun M, Brown M,Cicalese L, Benedetti E.  Immunosuppression through blockade of transferrin receptor: mechanisms.  Transplant. Proc 33(7-8):3279, 2001.
  44. Brown M, Braun M, Mercado P,Cicalese L, Benedetti E, Rastellini C.  Pyruvate improves pancreatic islet engraftment and functionality.  Transplant Proc 33(7-8):3523, 2001.
  45. Sileri P, Schena, S, Fukada J, Rastellini C, Pirenne J, Benedetti E, Cicalese L. Corticosteroids enhance hepatic injury following ischemia-reperfusion.  Transplant Proc 33(7-8):3712, 2001.
  46. Rastellini C, Braun M, Cicalese L, Benedetti E.  Construction of an optimal facility for clinical pancreatic islet isolation.  Transplant Proc 33(7-8):3524, 2001.
  47. Benedetti E., Sileri P., Pursell KJ, Giacomoni A., Tzoracoleftherakis E, Rastellini C, Cicalese L. Treatment of severe pneumonia in kidney transplant recipients.  Transplant Proc 33(7-8):3652, 2001.
  48. Cicalese L, Sileri P, Green M, Abu-Elmagd K, Kocoshis S, Reyes J. Bacterial translocation in clinical intestinal transplantation.  Transplantation 27; 71(10):1414-7, 2001.
  49. Cicalese L. Pyruvate in organ transplantation.  J Parenteral Enteral Nutri. 25(4):216-218, 2001.
  50. Cicalese L, Sileri P, Asolati M, Rastellini C, Abcarian H, Benedetti E.  Low infectious complications in segmental living related small bowel transplantation in adults.  ClinTransplant 14(6)567-71, 2000.
  51. Morini S, Braun M, Cicalese L, Gaudio E, Benedetti E, Rastellini C.  Isolated pancreatic islets: structural and ultrastructural analysis.  Transplant Proc 33(1-2):668-9, 2001.
  52. Rastellini C, Zuber V, Perrone G, Cicalese L, Gaudio E, Benedetti E, Morini S.  Revascularization and remodeling of transplanted pancreatic islets.  Transplant Proc 33(1-2):658-9, 2001.
  53. Rastellini C, Braun M, Li X, Blanchard J, Milewski S, Brown M, Cicalese L, Benedetti E. Prolongation of pancreatic islet graft survival by blocking transferrin receptor (CD71).  Transplant Proc 33(1-2):518-9, 2001.
  54. Li X, Cicalese L, DeMasi M, Benedetti E, Rastellini C.  Mechanisms underlying the immunosuppressive activity of anti-transferrin receptor monoclonal antibody.  Transplant Proc 33(1-2):136, 2001.
  55. Cicalese L, M Braun, P Sileri, S Morini, C Rastellini, E Benedetti. Pyruvate inhibits functional changes following intestinal ischemia/reperfusion injury. Surg Forum LI: 327-328, 2000.
  56. Cicalese L, Sahai A, Sileri P, Rastellini C, Subbotin V, Ford H, Lee K.  Acute pancreatitis and bacterial translocation. Dig Dis Sci 46(5):1127-1132, 2001.
  57. Karman J, Sileri P, Kamuda D,Cicalese L, Rastellini C, Wiley T, Layden T, Benedetti E. Risk factors for failure to meet listing requirements in liver transplant candidates with alcoholic cirrhosis. Transplantation 71(9):1210-3, 2001.
  58. Cicalese L, Baum C, Brown M, Sileri P, Smith D, Abcarian H, Benedetti E. Segmental small bowel transplant from adult living related donors.  Transplant Proc 33(1-2):1553, 2001.
  59. Benedetti E, Rastellini C, Sileri P, Asolati M, Milenski S, Vasquez E, Cicalese L. Successful simultaneous pancreas kidney transplantation from well-matched living related donors.  Transplant Proc 33(1-2):1689, 2001.
  60. Cicalese L, Sileri P, Asolati M, Rastellini C, Abcarian H, Benedetti E. Infectious complications following living related small bowel transplantation in adults.  Transplant Proc 33(1-2):1554-5, 2001.
  61. Sileri P, Brown M, Morini S, Rastellini C, Benedetti E, Cicalese L. Pyruvate prevents intestinal functional changes following ischemia-reperfusion injury. Transplant Proc 33(1-2):852, 2001.
  62. Sileri P, Schena S, Morini S, Rastellini C, Pham S, Benedetti E, Cicalese L. Pyruvate inhibits hepatic ischemia/reperfusion injury in rat.  Transplantation 72(1):27-30, 2001.
  63. Benedetti E, Baum C, Cicalese L, Brown M, Raofi V, Massad MG, Abcarian H. Progressive functional adaptation of segmental bowel graft from living related donor.  Transplantation 71(4):569-571, 2001.
  64. Cicalese L, Sileri P, Green M, Abu-Elmagd K, Fung JJ, Starzl TE, Reyes J. Bacterial translocation in clinical intestinal transplantation. Transplant Proc 32(6):1210, 2000.
  65. Cicalese L, Kuddus R,. Yacoub W, Subbotin V, Fung JJ, Starzl TE.  Ischemia/reperfusion injury induces chronic changes in the small bowel.  Transplant Proc 32(6):1315, 2000.
  66. Benedetti E, Braun M, Raofi V, Rastellini C, Baum C, Massad M, Abcarian H, Cicalese L. Living related small bowel transplantation: progressive functional adaptation of the graft. Transplant Proc 32(6):1209, 2000.
  67. Morini S, Yacoub W, Rastellini C, Gaudio E, Watkins S, Cicalese L. Intestinal microvascular patterns during hemorrhagic shock. Dig Dis Sci 45(4):710-722, 2000.
  68. Cicalese L, Giacomoni A, Rastellini C, Benedetti E.  Pancreatic transplantation: a review.  Intl Surg 84(4):305-12, 1999.
  69. Sileri P, Rastellini C, Dicuonzo G, Gaspari A, Benedetti E, Cicalese L. Small bowel transplantation and bacterial translocation: a review. Il Giornale di Chirurgia  21(4):196-204, 2000.
  70. Sileri P, Sica GS, Rastellini C, Dicuonzo G, Gaspari AL, Cicalese L. Traslocazione batterica e sua rilevanza chirurgica (Bacterial translocation and its surgical implications) Il Giornale di Chirurgia 20(10):440-4, 1999.
  71. Cicalese L, Subbotin V, Rastellini C, Stanko RT, Rao AS, Fung JJ. Preservation injury and acute rejection of small bowel grafts in the rat: protection afforded by pyruvate.  J Gastrointest Surg 3:549-554, 1999.
  72. Cicalese L, Yacoub W, Rogers JJ, Fung JJ, Rao AS, Starzl TE.  Translocation of bacteria from the GI tract: protection afforded by lisofylline.  Transplant Proc 31(1-2):575-6, 1999.
  73. Cicalese L, Yacoub W, Subbotin V, Fung JJ, Stanko R, Rao AS.  Pyruvate inhibits the chronic damage which ensues after ischemia/reperfusion injury of kidneys.  Transplant Proc 31:(1-2):1033, 1999.
  74. Cicalese L, Nussler NC, Hoffman RA, Neuhaus P, Schraut WH. Phenotypic and functional characteristic of intestinal intraepithelial lymphocytes during acute rejection of small intestinal allografts. Transplant Intl 11(2):102-109, 1998.
  75. Cicalese L, Aitouche A, Ploskina T, Ford H, Rao AS.  The role of laparotomy, gut manipulation and immunosuppression on bacterial translocation from the intestinal tract. Transplant Proc 31(4):1922-3, 1999.
  76. Rastellini C, Cicalese L, Leach R, Braun M, Fung JJ, Starzl TE, Rao AS.  Prolonged survival of transplanted islets in allogeneic recipients treated with tacrolimus (FK506) and leflunomide (Lef).  Transplant Proc 31(1-2):646-7, 1999.
  77. Cicalese L, Abu-Elmagd K, Bueno J, Todo S, Reyes J.  Intestinal transplantation in children after primary liver transplantation.  Transplant Proc 30(6):2680-1, 1998.
  78. Kaliff CJ, Cicalese L, Exner B, Schraut WH, Bauer AJ.  Role of phagocytes in causing dysmotility after each stage of small bowel transplantation.  Transplant Proc 30(6):2568, 1998.
  79. Cicalese L, Hierholtzer C, Subbotin V, Iynegar A, Rao AS, Stanko R.  The protective effect of pyruvate during acute rejection of intestinal allografts is accompanied by up-regulation of inducible nitric oxide synthase (iNOS) mRNA.  Transplant Proc 1997, 29(3):1813-4.
  80. Cicalese L, Billiar T, Rao AS, Bauer AJ.  Interaction between I/R-induced leukocyte emigration and translocating bacterial enterotoxins on enteric muscle function.  Transplant Proc 1997, 29(3):1815.
  81. Cicalese L, Iyengar A, Subbotin V, Aituche A, Rastellini C, Rao AS, Stanko RT.  Protection afforded by pyruvate during acute rejection of small bowel allografts is mediated by inhibition of oxygen free radicals and cytolytic activity (perforine and granzyme-B mRNA expression) of activated leukocytes.  Transplant Proc 29 (1-2):704, 1997.
  82. Cicalese L, Lee KKW, Schraut WH, Watkins S, Borle A, Stanko RT.  Pyruvate prevents post-ischemic mucosal reperfusion injury of the rat small bowel. Am J Surg, 171:87-101, 1996.
  83. Cicalese L, Caraceni P, Nalesnik MA, Borle AB, Schraut WH. Oxygen free radical content and neutrophil infiltration are important determinants in mucosal injury after rat small bowel transplantation. Transplantation 62(2):161-166, 1996.
  84. Cicalese L, Rastellini C, Rao AS, Stanko RT. Pyruvate prevents mucosal reperfusion injury, oxygen free radical production and neutrophil infiltration after rat small bowel preservation and transplantation. Transplant Proc 28(5): 2611, 1996.
  85. Cicalese L, Freswick P, Watkins S, Kelly AS, Rao AS, Stanko RT. The use of CD 14 and LBP mRNA expression in rat small bowel transplantation as markers for acute rejection.  Transplant Proc 28(5): 2470, 1996.
  86. Cicalese L, Subbotin V, Rastellini C, Rao AS, Stanko RT. Acute rejection of small bowel allografts in rats: protection afforded by pyruvate.  Transplant Proc 28(5): 2474, 1996.
  87. Cicalese L, Weber K, Lee R, Rakela J, Tabasco Minguillan J.  Effect of FK506 on the mucosal perfusion of the rat intestinal allograft during acute rejection.  Transplant Proc 28(5): 257, 1996.
  88. Tabasco Minguillan J, Cicalese L, Weber K, Lee R, Rakela J.  Mucosal reactivity of the intestinal allograft during acute rejection.  Transplant Proc 28 (5): 2576-2577, 1996.
  89. Tabasco Minguillan J, Cicalese L, Weber K, Lee R, Rakela J.  Mucosal perfusion in the rat intestinal allograft during acute rejection.  Transplant Proc 28(5): 2578-2580, 1996.
  90. Nussler NC,Cicalese L, Hoffman RA, Rastellini C, Neuhaus P, Simmons RL, Schraut WH. CD8+ host cells infiltrate the intestinal mucosa after allogeneic small bowel transplantation even in absence of acute rejection.  Transplant Proc 28(5): 2456, 1996.
  91. Cicalese L, Halfter WM, Heeckt PF, Schraut WH, Bauer AJ.  Immunocytes infiltration of the graft muscularis and its effect on muscle function during acute rejection of rat small intestinal allografts.  Transplant Proc 28(5): 2459, 1996.
  92. Cicalese L, Duerr R, Nalesnik M, Heeckt P, Lee KKW, Schraut WH. Decreased mucosal IgA levels in the ileum of patients with chronic ulcerative colitis.  Dig Dis Sci 40:(4):805-811, 1996.
  93. Tabasco Minguillan J,Cicalese L, Lee RG, Rakela J.  Mucosal perfusion and reactivity of the rat small intestinal allograft; effect of acute rejection.  Transplantation 60(12): 1572-1577, 1995.
  94. Rastellini C, Cicalese L, Zeevi A, Mattes C, Stanko RT, Starzl TE, Rao AS. Long-term culture of viable human pancreatic islets in pyruvate rich medium. Transplant Proc 27(6): 3383-3384, 1995.
  95. Cicalese L, Caraceni P, Nalesnik M, Lee K, Van Thiel DH, Schraut WH.  Oxygen free radicals formation is related to mucosal injury during reperfusion after rat small bowel transplantation.  Transplant Proc 26(3):1477, 1994.
  96. Darko K, Freeswik PD, Bartoli F, Cicalese L, Bardsley BA, Tzakis A, Nussler A.  A new technique for isolating and culturing human hepatocytes from whole or split livers unsuitable for liver transplantation. Cell Transplant 3(5):387-395, 1994.
  97. Cugini P, Lucia P, Poli L, Pisani G, Cicalese L, Salanitro C, Rastellini C, Di Nicuolo A, Iappelli M, Casciaro G, Pretagostini R, Berloco P, Alfani D, Cortesini R. Twenty-four hours blood pressure monitoring in kidney grafted patients with multiple renal arteries. Transplant Proc 25(3)2332-2333, 1993.
  98. Cortesini R, Alfani D, Berloco P, Caricato M, Casciaro G, Cicalese L, Iappelli M, Pisani G, Poli L, Pretagostini R, Rossi M, Salanitro C, Urbano D.  Surgical aspects in multiorgan transplantation: personal experience. Giornale di Chirurgia XI(10):527-533, 1993.

Educational Background:

Convitto Nazionale Vittorio Emanuele II Roma Italy "Diploma maturita'Classica"

University of Rome "La Sapienza", Rome Italy, Medical Doctor (MD)

University of Rome "La Sapienza", Rome Italy, General Surgery Residency

University of Pittsburgh, PA USA, Transplant Fellowship


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